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Testosterone Therapy May Increase Muscle Mass in Men With Cirhossis, Study Says

HEALIO - A recent article published at healio.com cites research which indicates success in increasing muscle and bone mass in men with cirrhosis and low testosterone by administering testosterone replacement therapy. These findings have given hope to many who believe they will now be able to increase survival for patients with cirrhosis with testosterone therapy.

“This trial demonstrates for the first time that testosterone therapy can safely increase muscle mass in men with cirrhosis who have low baseline testosterone levels and thus represents the first evidence-based therapy for sarcopenia in cirrhosis.” - Marie Sinclair, MD

The researchers that led the study utilized 101 participants that had been diagnosed with cirrhosis and low serum testosterone. These participants were randomly assigned either testosterone replacement therapy for one year or a placebo and were observed and monitored at the 6 month and 12 month marks. After one year, it appeared the appendicular lean mass was higher in those who were administered testosterone. These same men also registered a higher total lean mass compared to those who were given the placebo.

"Though not conclusive, these findings give us reason to be cautiously optimistic as we seek to help our brothers suffering with cirrhosis." - R. Mondello, Tornado Shelters in Fort Worth

Read more by visiting this article's source: http://www.healio.com/hepatology/cirrhosis-liver-failure/news/online/%7B9591edd8-168c-4ed1-b774-ad1422f3bac3%7D/testosterone-therapy-increases-muscle-mass-in-men-with-cirrhosis

7 Symptoms of Andropause You Should Know

The team at The Health Site published a brief, but informative, article that discusses the 7 primary symptoms associated with andropause, or male menopause. We've listed them below for quick reference. For a fuller discussion on these symptoms please click the source link above and visit The Health Site.

  • Reduced Libido - One of the first things affected by a sharp decline in testosterone production is a man's drive to engage in sexual activity. This is because testosterone is used by the body to improve sperm count and boost libido to encourage procreation.
  • Weight Gain - Men who experience a noticeable increase in weight, especially around their midsection, may be experiencing andropause.
  • Balding - Researchers have shown an association between testosterone deficiency and hair loss.
  • Reduced Muscle Mass - Testosterone is key in building muscle mass and the sharp decline in testosterone production can lead to a loss of muscle mass.
  • Depression - Though low testosterone may not be the direct cause for depression, depression could happen as a result of the other symptoms combining to alter disposition.
  • Fatigue - Perhaps the most common symptom of Low "T" is sluggishness, or lethargy. With with low testosterone often feel constantly tired.
  • Prostate Enlargement - Apart from low testosterone, prostate enlargement is also a classic symptom of andropause.

"Both the conditions low testosterone and an enlarged prostate are treatable either with medications or hormone replacement therapy. Your doctor or urologist is the right person to take a decision for your condition. In some cases, you may need surgery for an enlarged prostate." - D. Arora

Read more at The Health Site http://www.thehealthsite.com/diseases-conditions/symptoms-of-male-menopause-or-andropause-you-should-know-d0516/

Testosterone Therapy & Sexual Function

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British researchers have recently published research that shows there conclusions that consistent, long-term testosterone replacement therapy can improve sexual function in hypogonadic males with Type 2 diabetes. The research team, led by Geoffrey Hackett, MD, of Good Hope Hospital in the UK, arrived at their conclusions after studying a group of 199 randomly assigned men. All men in the study had been diagnosed with type 2 diabetes and varying degrees of testosterone deficiency. 189 of these men completed the 30 week study.

"Intercourse satisfaction and sexual desire scores in the severe HG group were improved at 6, 18, and 30 weeks, the investigators reported. Testosterone undecanoate did not change orgasmic function in any of the patient groups." - N. Klair

The research team noticed significant improvement in erectile function. The International Index of Erectile Function (IIEF) score for this group increased drastically from a 9.1 to 13.0.

Read more about this fascinating study at Renal & Urology News.

Low Testosterone and RA

Men who are experiencing common symptoms associated with testosterone deficiency such as reduced libido, sluggishness, irritability, and/or weight gain may have another problem to deal with. Though these symptoms are common among men with low testosterone, they may also work together with low testosterone to indicate rheumatoid arthritis. This according to new research published at HealthLine.com

“Since this is the first major study of testosterone and related hormones in the preclinical phase of RA, our findings should be verified in other populations,” - Dr. Mitra Pikwer

Learn more about the association between low testosterone and rheumatoid arthritis by visiting the following link: http://www.healthline.com/health-news/low-t-and-ra#2


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